Press Release

19.02.2020

Novel 3D lung tissue model for lung ageing receives research funding

Mareike Lehmann (left) and LRR Head Melanie Königshoff

Dr. Mareike Lehmann, Project Leader in the Lung Repair and Regeneration Unit (LRR), receives research funding from the German Centre for the Protection of Laboratory Animals (Bf3R) to develop an innovative human cell culture model for lung ageing.

The Bf3R is part of the Federal Institute for Risk Assessment. It is funding the work of Dr. Mareike Lehmann with 240,000 euros over three years including the funding of a PhD student. Lehmann is a member of Prof. Dr. Dr. Melanie Königshoff's unit LRR at the CPC-M, one of the sites of the German Center for Lung Research (DZL) and investigates the development of chronic lung diseases that mainly occur in elderly patients. The scientists previously demonstrated that cellular ageing mechanisms are essential contributors for the development of lung fibrosis. Lehmann's goal is to develop a novel human 3D- model for environmentally-induced lung ageing and age-associated chronic lung diseases that will allow to further reduce and replace animal experiments.

https://www.bfr.bund.de/en/german_centre