Observing complex systems at different scales (organisms to ecosystems) with high chemical resolution gives us new insights and understanding of generic processes across biology and geochemistry.

We aim at describing the metabolites chemodiversity of highly dynamic systems in health and environment with the tools of metabolomics and metallomics. The results of each individual project are going to be integrated in a comprehensive metabolite database involving exact masses from our direct infusion ICR-FT/MS (in ESI(-/+)), outcome of harmonized UPLC-qToF/MS methods (in ESI(-/+)) using reversed and HILIC phases and high-resolution cryo-800MHz NMR spectroscopy. Following this approach systematically over all various matrices with the same SOP enables us to setup a growing cross-kingdom metabolite database as the basis of metabolite cartography. In environmental systems the superimposition of biotic and abiotic transformations adds in complexity and chemodiversity. Here systematic analyses of purely chemical synthesized systems (Fischer-Tropsch, Maillard, photochemistry, oxidative polycondensations, thermochemical sulfate reduction, etc.) enable us to fulfil the chemical puzzle together with our metabolomics expertise in biotransformations.