Metallomics - Elements and Element Speciation

The special role of trace elements in biology and medicine is known for a long time. Trace elements and their binding forms, called element species, play an important role in biochemistry and metabolism of the organism. Element species can be metallo proteins (e.g. Cu-, Zn-metallothionein, glutathione peroxidase (Se-species), arginase (Mn-species), Thyroid hormones (I-species) or small organo metal complexes (e.g. Mn-, Fe-citrates).

The effect of trace elements decisively depends on their specific binding forms. Different species of an element are differently bioavailable, show different catalytic effects in the regulated metabolism or can have varying toxicity.
The analysis of element species is used to examine important conjunctions between trace elements or element species and the state of health, and particularly the metabolism of element species with diseases.

The working group Metallomics-Elements and Element Speciation pursues element species analytics problem-oriented predominantly in the medical-biological area.
Relationships between health problems and trace element species are examined, analytical methods are problem-oriented developed and innovative research projects are conceptualized.