Separation Science

Seperation Science

Over the last decades we initiated a series of developments around new chromatographic/electrophoretic monolithic materials or developed new concepts in sample preparation with magnetic nanoparticle materials. Our latest development is capillary electrokinetic concentration (CEKC) that extracts selective compounds out of a complex mixture based on charge density principles; this semi-preparative approach can be coupled to (ultrahigh resolution) mass spectrometry. In UHPLC/HR-MS the developments integrate new dopants for sensitivity improvements in Metabolomics as well as modelizations of both the compound specific chromatographic separation (HILIC and RP) and the mass fragmentation patterns (MetFrag).


Source: Helmholtz Zentrum München