Research Group Hagn

Franz Hagn

Prof. Hagn's (*1977) research is focused on nuclear magnetic resonance (NMR) spectroscopy of membrane proteins. This protein class is essential for signal transduction and the transfer of proteins and small molecules across the biological membrane barrier. The key to understanding these processes is to study these systems in a native environment provided by a phospholipid bilayer.

Biologically relevant systems of interest are mitochondrial membrane proteins, G-protein coupled receptors (GPCRs) and their associated G-proteins, which are involved in metabolic diseases, neurological disorders and cancer.

 

Prof. Hagn studied biochemistry at the universities of Bayreuth and Stockholm and moved to TUM to pursue his doctorate on structural and functional studies of molecular chaperones, tumorsuppressor and spider silk proteins. After a short postdoctoral stay at TUM, he went to Harvard Medical School, where he worked on the development of native membrane mimics for the structure determination of membrane proteins using NMR. In the fall of 2014 he accepted a Rudolf-Mössbauer assistant professorship of Structural Membrane Biochemistry at the TUM Institute for Advanced Study.

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