Selected publications


Wimmer P, Berscheminski J, Blanchette P, Groitl P, Branton PE, Hay RT, Dobner T Schreiner S. PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor suppressor p53. Oncogene 2015


Schreiner S, Günther T, Tessmer U, Dobner T and Grundhoff A. Influence of ND10 Components on the Epigenetic Determination of Early Kaposi´s Sarcoma-Associated Herpesvirus Latency. PLoS Pathog. 2014; 10(7):e1004274

Berscheminski J, Wimmer P, Brun J, Ip WH, Horlacher T, Groitl P, Jaffray E, Hay RT, Dobner T and Schreiner S. Sp100 isoform-specific regulation of human Adenovirus type 5 (Ad5) gene expression. J Virol. 2014; Jun;88(11):6076-92.

Castillo-Villanueva E, Ballesteros G, Schmid M, Hildago P, Schreiner S, Dobner T, and Gonzalez R. Mre11 cellular protein is modified by conjugation of both SUMO1 and SUMO2/3 during adenovirus infection. ISRN Virology 2014

before 2014

Schreiner S, Kinkley S, Bürck C, Mund A, Wimmer P, Schubert T, Groitl P and Dobner T. SPOC1-mediated antiviral host cell responses antagonized early in Human Adenovirus type 5 infection. PLoS Pathog.  2013; 9(11):e1003775.

Cheng C, Gilson T, Wimmer P, Schreiner S, Ketner G, Dobner T, Branton P and Blanchette P. The functional role of E1B55K in the E4orf6/E1B55K E3 ligase complexes formed by different human adenovirus serotypes. J Virol. 2013; Jun;87(11):6232-45.

Schreiner S, Bürck C, Glass M, Groitl P, Wimmer P, Kinkley S, Mund A, Everett RD and Dobner T. Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes. Nucleic Acids Res. 2013; 41(6):3532-50.

Berscheminski J, Groitl P, Dobner T, Wimmer P and Schreiner S. The adenoviral oncogene E1A-13S interacts with a specific isoform of the tumour suppressor PML to enhance viral transcription. J Virol. 2013; 87(2):965-77.

Wimmer P, Blanchette P, Schreiner S, Ching W, Groitl P, Berscheminski J, Branton P, Will H, Dobner T. Cross-talk between Phosphorylation and SUMOylation regulates transforming activities of an adenoviral Oncoprotein. Oncogene 2013; 28;32(13):1626-37.

Müller D, Schreiner S, Schmidt M, Groitl P, Winkler M and Dobner T. Functional cooperation between HAdV5 early region 4 reading frame 6 protein and cellular homeobox protein HOXB7. J Virol. 2012; 86(15):8296-308.

Schreiner S, Martinez R, Groitl P, Rayne F, Vaillant R, Wimmer P, Bossis G, Sternsdorf T, Ruzsics Z, Dobner T, Wodrich H. Transcriptional activation of the adenoviral genome is mediated by capsid protein VI. Plos Path. 2012; 8(2). e1002549.

Schreiner S, Wimmer P, Groitl P, Chen SY, Blanchette P, Branton PE, Dobner T. Adenovirus type 5 early region 1B 55K oncoprotein dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cells. J Virol. 2011; 85(17):8752-65.

Schreiner S, Wimmer P, Everett RD, Sirma H, Groitl P, Dobner T. 2010. SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PML. Oncogene; 2010; 29(40):5511-22.

Schreiner S, Wimmer P, Sirma H, Everett R, Blanchette P, Groitl P, Dobner T. Proteasome-dependent degradation of Daxx by the viral E1B-55K protein in human adenovirus-infected cells. J Virol. 2010; 84(14):7029-38.

Schreiner S, Kindsmüller K, Leinenkugel F, Groitl P, Kremmer E, Dobner T. A 49-kilodalton isoform of the adenovirus type 5 early region 1B 55-kilodalton protein is sufficient to support virus replication. J Virol 2009; 83(18):9045-56.

Selected Reviews

Schreiner S, Wodrich H. Virion factors that target Daxx to overcome intrinsic immunity. J Virol. 2013; 87(19):10412-22.

Schreiner S, Wimmer P and Dobner T. Adenovirus degradation of cellular proteins. Future Microbiology 2012; 7(2):211-225.

Wimmer P, Schreiner S and Dobner T. Human pathogens and the host cell SUMOylation system. Review. J Virol. 2011; 86(2):642.