ZYTO investigates radiation induced chromosome and DNA damage in cell systems and human tumors. The focus is on mechanisms associated with radiation-induced carcinogenesis and radiation sensitivity of tumor cells, aiming at the identification of radiation biomarkers and the stratification of personalized radiation therapy.

Chromosomal alterations and DNA damage
 induced by ionising radiation

Radiocarcinogenesis
Candidate genes and molecular mechanisms in radiation induced thyroid tumors

Radiation Sensitivity
Biomarkers for stratification of patients in personalised radiotherapy for HNSCC

Integrative Biology
Multilevel integration for the identification of radiation biomarkers and marker networks

Developing research tools
Red shifted variants of fluorescent protein eqFP615 for whole body imaging

Our Focus

  • The Research Unit Radiation Cytogenetics (ZYTO) investigates radiation-induced chromosome and DNA damage in cell systems and human tumours. The focus is on clarifying the mechanisms associated with radiation-induced carcinogenesis and radiation sensitivity of tumour cells. The aim of this research is to find biomarkers associated with radiation-induced tumours in order to develop personalized radiation therapy for the stratification of patients. ZYTO is a part of the Department of Radiation Sciences (DRS).