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Impairment and/or loss of pancreatic islet beta cells are at the origin of all forms of diabetes, leading to increased blood glucose levels. Scientists of the Institute for Pancreatic Islet Research (IPI/PLID) are working to decipher the causal mechanisms for these deficiencies with the aim of developing new approaches to protect or restore beta cell function and viability.
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Recent Publications
Here you can find the 10 latest publications of our institute. If you are looking for older publications, please follow the link below to our publications.
Ahuja et al., Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis. Diabetes Care. 2021 Apr;44(4):1062-1069. doi: 10.2337/dc20-1688.
Ansarullah et al., Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia. Nature. 2021 Apr;592(7852):E1. doi: 10.1038/s41586-021-03347-z.
Durán et al., Nonlinear machine learning pattern recognition and bacteria-metabolite multilayer network analysis of perturbed gastric microbiome. Nat Commun. 2021 Mar 26;12(1):1926. doi: 10.1038/s41467-021-22135-x.
Bornstein et al., The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease. Horm Metab Res. 2021 Mar;53(3):204-206. doi: 10.1055/a-1377-6583. Epub 2021 Mar 2.
Henke et al., Low-fat hypocaloric diet reduces neprilysin in overweight and obese human subjects. ESC Heart Fail. 2021 Feb 27. doi: 10.1002/ehf2.13220.
Bornstein et al., Consequences of the COVID-19 pandemic for patients with metabolic diseases. Nat Metab. 2021 Feb 25. doi: 10.1038/s42255-021-00358-y.
Bonifacio et al., An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood. Diabetes Care. 2021 Feb 24:dc202122. doi: 10.2337/dc20-2122.
Sormendi et al., HIF2α is a Direct Regulator of Neutrophil Motility. Blood. 2021 Feb 22:blood.2020007505. doi: 10.1182/blood.2020007505.
Lagou et al., Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC). Nat Commun. 2021 Feb 8;12(1):995. doi: 10.1038/s41467-021-21276-3.
Hu et al., Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion. Cell Rep. 2021 Feb 2;34(5):108703. doi: 10.1016/j.celrep.2021.108703.
