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Impairment and/or loss of pancreatic islet beta cells are at the origin of all forms of diabetes, leading to increased blood glucose levels. Scientists of the Institute for Pancreatic Islet Research (IPI/PLID) are working to decipher the causal mechanisms for these deficiencies with the aim of developing new approaches to protect or restore beta cell function and viability.
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Recent Publications
Here you can find the 10 latest publications of our institute. If you are looking for older publications, please follow the link below to our publications.
- Peitzsch et al., Metabolic regulation of prostate cancer heterogeneity and plasticity. Semin Cancer Biol. 2020 Dec 5:S1044-579X(20)30261-3. doi: 10.1016/j.semcancer.2020.12.002. Online ahead of print.
- Marselli et al., Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes. Cell Rep. 2020 Dec 1;33(9):108466. doi: 10.1016/j.celrep.2020.108466
- Ziegler and Bonifacio. Shortening the paths to type 1 diabetes mellitus prevention. Nat Rev Endocrinol. 2020 Nov 30. doi: 10.1038/s41574-020-00450-5.
- Noseda et al., MT2 melatonin receptors expressed in the olfactory bulb modulate depressive-like behavior and olfaction in the 6-OHDA model of Parkinson's disease. Eur J Pharmacol. 2020 Nov 5:173722. doi: 10.1016/j.ejphar.2020.173722.
- Hippich et al., Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children. Med (N Y). 2020 Oct 29. doi: 10.1016/j.medj.2020.10.003.
- Imam et al., Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study. Front Physiol. 2020 Oct 9;11:564140. doi: 10.3389/fphys.2020.564140.
- Chen et al., Platelet Glycoprotein VI dependent Thrombus Stabilization is Essential for the Intraportal Engraftment of Pancreatic Islets. Am J Transplant. 2020 Oct 25. doi: 10.1111/ajt.16375.
- Chwastek et al., Principles of Membrane Adaptation Revealed through Environmentally Induced Bacterial Lipidome Remodeling. Cell Rep. 2020 Sep 22;32(12):108165. doi: 10.1016/j.celrep.2020.108165.
- Stazi etal., Melatonin promotes regeneration of injured motor axons via MT1 receptors. J Pineal Res. 2020 Sep 17:e12695. doi: 10.1111/jpi.12695. Online ahead of print.
- Kaptan et al., Exogenous ethanol induces a metabolic switch that prolongs the survival of Caenorhabditis elegans dauer larva and enhances its resistance to desiccation. Aging Cell. 2020 Sep 8:e13214. doi: 10.1111/acel.13214.
