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Impairment and/or loss of pancreatic islet beta cells are at the origin of all forms of diabetes, leading to increased blood glucose levels. Scientists of the Institute for Pancreatic Islet Research (IPI/PLID) are working to decipher the causal mechanisms for these deficiencies with the aim of developing new approaches to protect or restore beta cell function and viability.
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Recent Publications
Here you can find the 10 latest publications of our institute. If you are looking for older publications, please follow the link below to our publications.
- Holthaus et al. Functional and metabolic fitness of human CD4+ T lymphocytes during metabolic stress. Life Sci Alliance. 2021 Sep 27;4(12):e202101013. doi: 10.26508/lsa.202101013. Print 2021 Dec.
- Pinter et al. Biologic Treatment in Combination with Lifestyle Intervention in Moderate to Severe Plaque Psoriasis and Concomitant Metabolic Syndrome: Rationale and Methodology of the METABOLyx Randomized Controlled Clinical Trial. Nutrients. 2021 Aug 29;13(9):3015. doi: 10.3390/nu13093015.
- Subramanian et al. The RNA binding protein HuR is a gatekeeper of liver homeostasis. Hepatology. 2021 Sep 14. doi: 10.1002/hep.32153.
- Nati et al. The Role of Innate Immune Cells in Nonalcoholic Fatty Liver Disease. J Innate Immun. 2021 Aug 24:1-11. doi: 10.1159/000518407.
- Kemter et al. Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2107665118. doi: 10.1073/pnas.2107665118.
- Watts et al. Transient Depletion of Foxp3+ Regulatory T Cells Selectively Promotes Aggressive β Cell Autoimmunity in Genetically Susceptible DEREG Mice. Front Immunol. 2021 Aug 10;12:720133. doi: 10.3389/fimmu.2021.720133.
- Spears et al. Debates in Pancreatic Beta Cell Biology: Proliferation Versus Progenitor Differentiation and Transdifferentiation in Restoring β Cell Mass. Front Endocrinol (Lausanne). 2021 Aug 6;12:722250. doi: 10.3389/fendo.2021.722250.
- Vvedenskaya et al. Non-alcoholic fatty liver disease Stratification by Liver Lipidomics. J Lipid Res. 2021 Aug 9:100104. doi: 10.1016/j.jlr.2021.100104.
- Tonnus et al. Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury. Nat Commun. 2021 Jul 20;12(1):4402. doi: 10.1038/s41467-021-24712-6.
- Schumann et al. Publisher Correction: Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance. Commun Biol. 2021 Jul 14;4(1):890. doi: 10.1038/s42003-021-02425-2.
