Nößner Lab
Research unit IMA-TCI studies the interaction of immunocytes with aberrant tissue cells in kidney liver and lung to provide new hypothesis for therapy improvement. Immune monitoring accompanying clinical trials shall identify new prognostic and predictive markers.
Research unit IMA-TCI studies the interaction of immunocytes with aberrant tissue cells in kidney liver and lung to provide new hypothesis for therapy improvement. Immune monitoring accompanying clinical trials shall identify new prognostic and predictive markers.
About our research
The focus of our research are immunocytes in peripheral blood and within tissue where they have to be active to maintain health and fight disease. We study killer cells in cancer patients. They are detected even in patients with advanced disease, thus, their activity is obviously not sufficient to destroy the cancer cells. We wish to understand the immune suppression and explore strategies to better activate the patients' immune system. We use engineering approaches and means to change the tissue milieu to enable necessary immune reactivity. With our knowledge in flow cytometry and multiplex cytokine profiling we determine the features of those immunocytes, which can destroy the cancer cells. We work closely with clinicians and pharma, providing our knowledge for guidance to improve therapies and help patient selection for best therapeutic approach.
Our scientists at Nößner Lab
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